Trusted Prescription Drug Information

• Do not stop taking Zyban without first talking to your doctor. It may be several weeks before you begin to feel better, and you may require continuous treatment for quite some time.
• Avoid alcohol or drink it only in moderation while taking Zyban. Alcohol may increase the risk of having a seizure while taking bupropion. However, if you usually drink a lot of alcohol, talk with your doctor before stopping. Suddenly stopping may increase the risk of having a seizure. Talk to your doctor about alcohol use before starting treatment with Zyban.
• Do not crush, chew, or break the sustained- or extended-release tablets (Wellbutrin SR, Wellbutrin XL, Zyban SR). Swallow them whole. They are specially formulated to release slowly in the body. If you are unsure of the formulation of your medication, ask your healthcare provider.
• Zyban may be used to treat different medical conditions. You should not be taking more than one product containing bupropion at a time (e.g., Wellbutrin and Zyban SR). Talk to your doctor if a second product containing bupropion is prescribed for you. Too much of this medicine can increase the risk of a seizure.
• Never take more Zyban in one dose or in one day than is directed by your doctor. Higher doses of bupropion may increase the risk of a seizure.